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Gynecologic Health Gynecologic Screening

Wanted: An Easy Test for Endometriosis


Medically Reviewed On: October 27, 2004

By Christine Haran

Although most women are all too familiar with cramping and bloating, women with endometriosis tend to experience pain that can interfere with their relationships and everyday activities. Endometriosis is a curious gynecological condition that occurs when cells that normally line the inside of the uterus break away and seed somewhere else in the body where they don't belong—sometimes as far away as the lungs. It can cause severe menstrual cramps and infertility as well as debilitating pain and may explain a host of nebulous complaints.

It's estimated that 5.5 million women in North America have endometriosis, but it's difficult to assess how common the condition truly is because surgery is required for a definitive diagnosis. While some women and their doctors choose to manage the condition with hormones without a confirmed diagnosis, others opt for the surgery.

Below, Tommaso Falcone, MD, chairman of obstetrics and gynecology at the Cleveland Clinic Foundation in Ohio, explains endometriosis symptoms and reviews current diagnostic tests and treatments, as well as the research devoted to finding an effective non-surgical way to diagnosis this disease.

What is endometriosis?
Endometriosis is defined as the presence of endometrial tissue, which is the tissue that is found on the lining of the uterus, outside of the uterus.

What are some common and uncommon locations for this tissue?
The common locations are the ovaries and the inside of the vagina in the so-called the cul-de-sac, which is the area of the deepest part of the pelvis, and the lining of the pelvis called the peritoneum.

There are circumstances where it is found at other sites. The most common area outside of the pelvis would be the intestine. It could be on the appendix, the liver or the lung. It's located on nerves such as the sciatic nerve, which is that big nerve in the leg. It's been reported pretty much everywhere in the body.

Patients will have different types of symptoms depending upon the location of the tissue. For example, if it involves the sciatic nerve, the patient can have leg pain and difficulties walking. Or if they have endometriosis on the intestine, they'll have intestinal symptoms, like constipation or diarrhea. If it's on the lung, they may go to a lung specialist with a collapsed lung. Then after they've had a biopsy, they wind up seeing a gynecologist.

What are the most common symptoms?
The most important symptom is pain, and then infertility. The pain part is usually very bad pain before or after the period and with sexual intercourse. Women may also have non-cyclic pelvic pain, which means it can come at any time.

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