There have been reports of self-injury and delirium in patients with influenza who used Tamiflu. Most of these reports are from Japan and occurred primarily among pediatric patients. Because of these reports, the revised patient information includes the following warning:
"People with the flu, particularly children, may be at an increased risk of self-injury and confusion shortly after taking TAMIFLU and should be closely monitored for signs of unusual behavior. A healthcare professional should be contacted immediately if the patient taking TAMIFLU shows any signs of unusual behavior."
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